DIM (Diindolylmethane) Full Review & In-Depth Look

Diindolylmethane is a molecule found in broccoli that, according to examine.com, consists of “two indole groups attached to a methane group” [1].

Aromatase Inhibitor

DIM has been touted by many in the scientific community as an excellent aromatase inhibitor, which means that it can prevent the conversion of Testosterone into Estrogen.

Because of this DIM (and broccoli) are very popular with bodybuilders.

This is because Aromatase can seriously affect a bodybuilder’s physique. The enzyme works by converting excess testosterone into estrogen, and because most bodybuilders are taking testosterone supplements (either legal or illegal) they are the most likely to be affected by aromatase.

Finding a supplement or ingredient that can inhibit or “block” aromatase is great news, because that excess testosterone will be left alone. Keeping testosterone levels high, and estrogen levels low. This means that bodybuilders will be able to build more muscle, increase protein synthesis, and keep their body fat levels low.

Overweight Men

DIM may also have benefits for overweight and obese men, as adipose tissue (body fat) tends to release aromatase, which can lead to a lowering of testosterone, and the development of female characteristics. Breast tissue can begin to form, and body fat can begin to accumulate around the abdominal region.

If you are obese then taking DIM on its own is probably not going to do too much to address your issues. However it will reduce estrogen and prevent further loss of Testosterone. DIM is most effective when it is combined with the three main pillars of a healthy life: Exercise, Diet, and Sleep.

Estrogen Fighting Foods

Add some DIM to a diet that contains a lot of estrogen fighting foods (cruciferous vegetables), and some testosterone boosting foods (celery, red meat etc), and it will be very effective.

As would an increase in sleep quality/duration, and the initiation of an exercise program.

Anti-Cancer Effect

Another benefit of DIM is its anti-cancer effect, reducing the risk of breast, cervical, uterine, and prostate cancer. Making it a great supplement choice for both men and women.

Side Effects

At the moment there doesn’t seem to be any side effects to taking DIM. Though it is used to reduce estrogen, it does this because it wants to balance your hormones.

So there is no danger of you lowering estrogen too much.

If you have a surplus of estrogen then supplementing with a DIM / anti-estrogen product will help you, but if you have normal or low amounts, it will not reduce it further.


According to examine.com [1], you should see a reduction in estrogen when taking 100mg of DIM. Though there have been no reported side effects of taking DIM in normal levels 2mg-100mg.

According to WebMD taking levels as high as 600mg can lead to reduced sodium levels [2].

As with any drug, stick to the dosage recommendation, don’t take loads, and contact your physician if you feel that this is necessary.

Bottom Line

DIM is a great supplement ingredient which has a lot of benefits, for both men and women.

It is as useful for highly trained bodybuilders as it is for completely sedentary, obese persons.

Definitely worth taking as a supplement, or consuming through a diet rich in cruciferous vegetables.


[1] https://examine.com/supplements/diindolylmethane/

[2] http://www.webmd.com/vitamins-supplements/ingredientmono-1049-diindolylmethane.aspx?activeingredientid=1049&activeingredientname=diindolylmethane

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