Managing the right level of estrogen production without the support of supplementation can be a tricky job; this is especially true when levels reach an excessive point.

Once estrogen levels reach that point there begins to be a negative affect on men, such as decreased testosterone production and its availability.

No man wants low testosterone and high estrogen, that’s a fact.

This is where anti-estrogen supplementation comes in; with the rapid growth in science research and information there have been the creation of some great estrogen blocking/reducing supplements that are readily available.

Check out our top 10 list below and find the top rated natural estrogen blocking supplements.

Starting with the lowest rated product first, scroll to the bottom for our top-rated supplement.


  1. DIM – Olmpian Labs

Olympian Labs kept it simple with the release of their DIM (Di-Indolyl-Methane) product. DIM is a potent single-ingredient product containing 150mg per serving (1 capsule daily) with a 30-day supply for an affordable price.

What is DIM? DIM is a food-based compound found in cruciferous vegetables such as broccoli, cabbage, cauliflower, etc. Why take DIM? Specifically, studies have suggested that taking DIM can inhibit the aromatase enzyme (and prevent the conversion of testosterone into estrogen) and it is also known to convert potent forms of estrogen into less potent forms; overall, DIM reduces the effects of estrogen in the body. However, note that more isn’t better when it comes to DIM, taking too much can have the opposite affect on the aromatase enzyme, which is what you do not want!

Highlights for Olympian Labs – DIM

  • Supports a healthy balance of testosterone to estrogen ratio
  • May help promote fat loss
  • Contributes to healthy metabolism in a natural way by supporting hormonal action

Order Olmpian Labs DIM for the best price at – Order Here

  1. Axis Labs – MYODEX

Axis Labs released MYODEX, their ‘advanced testosterone modulator’. Axis Labs claims that the MYODEX formula was made to promote a healthy balance of DHT (dihydrotestosterone) and estrogren and to support product of testosterone.

One of the reasons MYODEX made the list is because of their “ Estrogen Inhibiting Complex” which features full strength Quercetin and DIM. As mentioned earlier, DIM may compete with estrogen and reduce the effects of estrogen.

We’ve covered DIM, but what is Quercetin? Simply put, Quercetin is a powerful flavonoid that functions as an antioxidant and has the effect of reducing aromatase enzymes, which simply means it may promote testosterone production and less estrogen production.

MYODEX is a great formula, but unfortunately contains a proprietary blend so we have no way of telling how much of each ingredient it contains, without that it can not be ranked any better.

Highlights for Axis Labs – MYODEX

  • Boost Testosterone
  • Promote DHT Balance
  • Support Estrogen Balance

Order Axis Labs MYODEX for the best price at – Order Here

  1. PEScience – ERASE PRO +

ERASE PRO + by PEScience has been recently reformulated. It contains all the same ingredients as before, except now with Ksm-66 Ashwagandha. ERASE PRO + is a great all-in-one hormone optimizer, however, the issue is in a proprietary blend which again is unfortunate because we cannot tell how much each ingredient contains.

The new ingredient, KSM-66® brand premium Ashwagandha has been tested numerous times and overall the results show that it is good for hormone support capabilities, especially Cortisol and Testosterone. Although we technically don’t consider ERASE PRO + to be a anti-estrogen category, overall it is a worthy hormone optimizer with a fair ingredient profile. However, for estrogen control, the product lacks and would not be as effective in this department.

Highlights for PEScience – ERASE PRO +

  • Boost testosterone levels
  • Optimize cortisol levels

Order PEScience ERASE PRO + for the best price at – Order Here


ESTROBLOCK was formulated as a complete hormone balance post-cycle formula. ESTROBLOCK is designed to help optimize testosterone levels and lower excess estrogen levels. It does this through the use of DIM, Panax Ginseng, and Chrysin.

What is good about ESTROBLOCK is the transparent label, so you know exactly what ingredients you’re getting and at what amounts. The downside to this product is the under dose of ingredients. The serving size it 1 capsule that is recommended to take 3 times daily. This is not only inconvenient but also expensive, as it will only take 20 days to use a full bottle.


  • Help balance testosterone/estrogen levels
  • Post-cycle testosterone support
  • Helps boost muscle growth & reduce water retention

Order DEVELOPT – ESTROBLOCK for the best price at – Order Here


Nolvadren XT is formulated as a 3-in-1-hormone modulator. It can be used to provide healthy testosterone and estrogen levels, along with a proper diet and exercise program of course.

Overall, the product ingredient label is fairly solid, with proven ingredients to naturally boost testosterone, reduce estrogen and cortisol leading to a leaner and harder looking physique.

The issue with this product is that the doses are a bit low. This product would also not be ideal for long-term use, as it has been reported that users have side effects such as joint pain and hot flashes with re-use of the product. For something long-term, check out our #1 choice!


  • Increase free testosterone levels
  • Boost performance
  • Helps manage estrogen and cortisol levels

Order MAN SPORTS – NOLVADREN XT for the best price at – Order Here

  1. Magnum Nutraceuticals – E-Break

    E-Break has a different approach as compared to most anti-estrogen supplements on the market. Magnum took a more “pharmaceutical” approach to this product, as they made some major revisions to their branding.

E-Break contains many estrogen-blocking ingredients, such as Acacetin & Pygeum Bark, which all come from plant extracts. Along with this, there are also a many other ingredients contained in the product to maintain proper hormonal balance. The list is great, however, at this time the ingredients sort of lack in conclusive research; in addition, the price-point is fairly high for a 24-serving size product.

Highlights for E-Brake

  • May help support estrogen balance
  • Support muscle growth & strength
  • Aid in fat loss
  • Optimize all aspects of physical performance

Order Magnum Nutraceuticals for the best price at – Order Here

  1. MTS Nutrition – Tyrant

Falling slightly behind E-Block, Tyrant is still a solid cortisol and estrogen control “hardening agent”. Containing 500mg of Green tea extract, 250mg of DIM. 200mg of Calcium d-Glucarate, Tyrant will is a great option for cortisol and estrogen control. However, Tyrant falls short on the ingredient doses, pushing it to #4 on our list.

Highlights for MTS Nutrition – Tyrant

  • Cortisol and Estrogen control
  • Hardening agent

Order MTS Nutrition Tyrant for the best price at – Order Here


  1. Pride Nutrition – E-Block

Making its mark and coming in at #3, E-Block by Pride Nutrition is a well-rounded estrogen formula that was formulated to help reduce and restore correct levels of hormone balance. E-Block is a solid formula comes up a little short on serving size, which is why it falls just short at #3.

Highlights for Pride Nutrition – E-Block

  • Regulate & restore hormone balance
  • Help eliminate cystic and hormonal acne
  • Help improve energy, focus, endurance, and sex drive

Order Pride Nutrition E-Block for the best price at – Order Here

  1. S.A.N. – CONQUEST 250

CONQUEST 250 is far from complicated, this may be a single serving product but it has huge potential. Ursolic acid is the key ingredient in this product and has multiple studies that have shown many positive results with its use. One study suggested that ursolic acid increased fat loss by 50%, and another suggest it reduces catabolism in lab animals by reducing estrogen levels. If you look to manage estrogen levels and increase muscle hypertrophy, then CONQUEST 250 may be a good option for you. See below for our #1 rank estrogen blocker.

Highlights for S.A.N. – CONQUEST 250

  • Control estrogen levels
  • Increase muscle growth
  • Help in fat loss

Order S.A.N. CONQUEST 250 for the best price at – Order Here


Jacked Factory is taking things to the next level with their scientifically dosed, proprietary-blend free, all-natural estrogen management supplement ANDROSURGE.

Because of the key ingredients, not only is this an anti-estrogen supplement, but it also helps booster natural testosterone. Overall, it’s an all-in-one hormone optimizer.

Jacked Factory is known for their clinically dosed products and they didn’t stop here. ANDROSURGE is dosed in amounts backed by science and it’s obvious that each ingredient is carefully selected with a purpose.

It’s clear that with ANDROSURGE, Jacked Factory wants to maximize user’s natural testosterone production without increasing estrogen production to excessive amounts.

The great thing we’d like to point out about ANDROSURGE is that it’s all-natural, so there is no need to worry about “cycling off” as opposed to other intense supplements that will shut down natural hormone production.

Jacked Factory manufactures all of their products in a cGMP facility in the USA, and are free from unnecessary additives. Unlike most, Jacked Factory offers a 100% money-back guarantee if for any reason you are not satisfied with your results.

Read our Androsurge full review and in-depth look here.

Highlights for Jacked Factory – ANDROSURGE



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